International art dealer Ron Hall must befriend a dangerous homeless man in order to save his struggling marriage to his wife, a woman whose dreams will lead all three of them on the journey of their lives.

Tim Blake Nelson (The Ballad of Buster Scruggs) is a man who's safe and comfortable and bored to death with his life. In his state of despair, he looks to classic stories for inspiration. Awakened by the tales of yore, he anoints himself as Don Quixote to find adventure, fame and glory that will make his life worthwhile - all while never leaving his one-mile square neighborhood.

To escape her abusive husband, Melissa hides with her son in the family chalet that has been uninhabited for years. But then one day in the park, her son disappears.